The Chicago Cubs meet the Pittsburgh Pirates within the third and ultimate recreation of their collection on Thursday. Chicago received Tuesday’s opener 9-0, earlier than Pittsburgh rallied for a 4-3 win on Wednesday. The Cubs (18-13), who lead the Nationwide League Central, have dropped three of 4. The Pirates (12-19), who’re fifth within the division, snapped a three-game shedding streak with the win.
First pitch from PNC Park in Pittsburgh is ready for 12:35 p.m. ET. The Cubs have received 5 of the final seven conferences towards the Pirates. Pittsburgh is a -125 favourite on the cash line (threat $125 to win $100) within the newest Cubs vs. Pirates odds from DraftKings Sportsbook, whereas the entire variety of runs Vegas thinks might be scored, or the over-under, is 8. Earlier than making any Pirates vs. Cubs picks, make sure to see the MLB predictions and betting recommendation from SportsLine’s confirmed pc mannequin.
The SportsLine Projection Mannequin simulates each MLB recreation 10,000 occasions. It enters Week 6 of the 2025 MLB season on a 17-11 run on top-rated MLB betting picks (+276). Anyone following at sportsbooks and on betting apps may have seen sturdy returns.
Now, the mannequin has set its sights on Cubs vs. Pirates and simply locked in its picks and MLB predictions. You possibly can head to SportsLine now to see the mannequin’s picks. Listed here are a number of MLB odds and betting strains for Cubs vs. Pirates:
- Cubs vs. Pirates cash line: Chicago +105, Pittsburgh -125 at DraftKings Sportsbook
- Cubs vs. Pirates over-under: 8 runs
- Cubs vs. Pirates run line: Pittsburgh -1.5 (+170)
- CHC: The below is 3-1-1 within the Cubs’ final 5 video games
- PIT: The below is 4-2-1 within the Pirates’ final seven video games
- Cubs vs. Pirates picks: See picks at SportsLine
- Cubs vs. Pirates streaming: FuboTV (Strive without cost)
Why the Pirates can cowl
Pittsburgh is predicted to ship ace right-hander Paul Skenes (3-2, 2.39 ERA) to the mound. He has made six begins on the season, pitching 37.2 innings and permitting 26 hits, 12 runs – 10 earned – and 4 walks with 39 strikeouts. In his final outing on Friday, he earned a win in a 3-0 victory over the Los Angeles Dodgers. In 6.1 innings, he allowed 5 hits, whereas placing out 9.
Shortstop Isiah Kiner-Falefa is amongst Pittsburgh’s high hitters this 12 months. In 30 video games, he’s hitting .280 with three doubles, one triple and 7 RBI. He has additionally stolen six bases. He was 2-for-4 in Tuesday’s loss to Chicago, registering his sixth multi-hit recreation of the 12 months. In 12 profession video games towards the Cubs, he has 10 hits, together with a double and 5 RBI. See which crew to again at SportsLine.
Why the Cubs can cowl
Chicago is predicted to counter with right-handed pitcher Colin Rea (1-0, 0.96 ERA). The veteran spent the final three seasons with the Milwaukee Brewers, and went 12-6 with a 4.29 ERA final season. In his final outing, a 4-0 win over the Philadelphia Phillies, he pitched 5 innings, permitting simply three hits and two walks with seven strikeouts to earn the victory.
Serving to energy the offense is correct fielder Kyle Tucker. The eighth-year veteran is among the many crew’s main hitters, batting .279 by 31 video games, with eight doubles, two triples, seven homers and 27 RBI. In an 11-10 win over the Dodgers on April 22, he was 3-for-4 with a homer, two RBI, two runs scored and two stolen bases. He has hit the Pirates properly. In 4 profession video games towards them, he’s batting .429 with a homer and 6 RBI. See which crew to again at SportsLine.
The best way to make Cubs vs. Pirates picks
SportsLine’s mannequin is leaning Over on the entire, projecting 9.4 mixed runs, and it says one facet of the cash line has all the worth. You possibly can head to SportsLine to see the mannequin’s MLB picks.
So who wins Cubs vs. Pirates, and which facet has all the worth? Go to SportsLine now to see which facet it’s essential soar on, all from the mannequin that has crushed its MLB picks, and discover out.
