The Detroit Tigers look to finish the three-game sequence sweep once they battle the Tampa Bay Rays in a key American League matchup on Wednesday. Detroit received 5-1 on Monday and 4-2 on Tuesday. The Rays (49-43), who’re third within the American League East, are 21-18 on the street this season. The Tigers (59-34), first within the AL Central, are 32-14 on their residence subject in 2025.

First pitch from Comerica Park in Detroit is about for five:10 p.m. ET. The Tigers have received seven of the final 10 conferences with the Rays. Detroitis a -150 favourite on the cash line (threat $150 to win $100) within the newest Rays vs. Tigers odds from DraftKings Sportsbook, whereas the overall variety of runs Vegas thinks shall be scored, or the over/below, is 8. Earlier than making any Rays vs. Tigers picks, remember to see the MLB predictions and betting recommendation from SportsLine’s confirmed laptop mannequin.

The SportsLine Projection Mannequin simulates each MLB sport 10,000 instances. It enters Week 16 of the 2025 MLB season 45-38 on top-rated MLB picks. It has excelled making residence run prop picks this season, returning greater than 28 models of revenue. Anyone following at sportsbooks and on betting apps may have seen sturdy returns.    

Now, the mannequin has set its sights on Rays vs. Tigers and simply locked in its picks and MLB predictions. You may head to SportsLine now to see the mannequin’s picks. Listed here are a number of MLB odds and betting strains for Tigers vs. Rays, which you will get in on with a DraftKings promo code or a FanDuel promo code.

Why the Tigers can win

Detroit is predicted to ship right-hander Reese Olson (4-3, 2.89 ERA) to the mound. In 10 begins this season, he has pitched 53 innings, permitting 44 hits, 17 earned runs and 20 walks with 54 strikeouts. He obtained a no-decision in his final outing, a 2-1 win at Cleveland on Friday. In that sport, he pitched 4.1 innings, permitting six hits, one earned run and one stroll with three strikeouts.

Second baseman Gleyber Torres is among the many offensive weapons for the Tigers. In 80 video games this season, he’s hitting .275 with 13 doubles, 9 homers and 44 RBI. He was 1-for-4 in Tuesday’s win over Tampa Bay. In an 11-7 loss to the Washington Nationals on Thursday, he was 2-for-4 with a stroll and an RBI. See which staff to again at SportsLine.

Why the Rays can win

Proper-hander Zack Littell (7-7, 3.50 ERA) is predicted to get the beginning for Tampa Bay. In 18 begins this season, he has logged 110.2 innings pitched, permitting 103 hits, 43 earned runs and 15 walks with 76 strikeouts. He obtained a no-decision in a 4-3 loss at Minnesota on Friday. In that sport, he pitched six innings, permitting 4 hits, one earned run and two walks with 5 strikeouts.

First baseman Jonathan Aranda has been purple sizzling within the sequence. In Tuesday’s loss to the Tigers, he was 2-for-4 with a double and residential run. He was 1-for-4 with an RBI in Monday’s defeat. In 87 video games this season, he’s hitting .321 with 18 doubles, 11 homers and 49 RBI. See which staff to again at SportsLine. 

make Rays vs. Tigers picks

SportsLine’s mannequin is leaning Over on the overall, projecting 9.1 mixed runs, and it says one aspect of the cash line has all the worth. You may head to SportsLine to see the mannequin’s MLB picks. 

So who wins Rays vs. Tigers, and which aspect of the cash line has all the worth? Go to SportsLine now to see which aspect it is advisable to bounce on, all from the mannequin that has crushed its MLB picks, and discover out.